Thermo Fisher Scientific ELK1 Monoclonal Antibody (PCRP-ELK1-1D9)
인간 ELK1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB 및 ICC/IF에 사용 가능. 고순도 Protein A/G 정제 제품이며, 액상 형태로 4°C 보관. 연구용으로 MAP kinase 신호전달 관련 연구에 적합.
- 카탈로그번호
- 2002-MSM2-P1
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-ELK1-1D9 |
| Immunogen | Recombinant full-length human ELK1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ELK1 is a component of the ternary complex that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. It is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus, with phosphorylation at Ser383 being critical for transcriptional activation. ELK1 acts as a direct target of activated MAP kinase and serves as a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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