Thermo Fisher Scientific SLC35D1 Polyclonal Antibody
SLC35D1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 0.02% sodium azide가 포함되어 있습니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 20 amino acid peptide near the carboxy terminus of the human Slc35D1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153340 |
Product Specific Information
- A suggested positive control is rat liver tissue lysate.
- PA5-20552 can be used with blocking peptide PEP-0672.
Target Information
The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum.
The ER-resident Slc family member Slc35D1 transports both UDP-glucuronic acid and UDP-N-acetylgalactosamine, which serve as substrates for chondroitin sulfate biosynthesis.
Mice lacking the Slc35D1 gene develop a lethal skeletal dysplasia with severe limb and facial shortening.
Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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