Thermo Fisher Scientific Palladin Polyclonal Antibody
Thermo Fisher Scientific의 Palladin Polyclonal Antibody는 인간 Palladin 단백질을 인식하는 토끼 IgG 항체입니다. Western blot과 Immunocytochemistry에 적합하며, 액상 형태로 제공됩니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 저장 및 높은 특이성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Palladin (Recombinant protein control fragment: RP-104663) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664239 |
Product Specific Information
Immunogen sequence:
NCSYESMGESN NDHFQHFPPP PPILETSSLE LASKKPSEIQ QVNNPELGLS RAALQMQFNA AERETNGVHP SRGVNGLING KANSNKSLPT P
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 83%
Target Information
Palladin is a cytoskeletal protein required for organization of the normal actin cytoskeleton. It plays roles in establishing cell morphology, motility, adhesion, and cell–extracellular matrix interactions. Palladin may act as a scaffolding molecule influencing actin polymerization and filament assembly. It binds to proteins associated with monomeric or filamentous actin and localizes at sites of active actin remodeling such as lamellipodia and membrane ruffles. Different isoforms of Palladin may have distinct functional roles. It is also involved in morphological and cytoskeletal changes during dendritic cell maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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