Thermo Fisher Scientific Palladin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

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Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Palladin. Recombinant protein control fragment (Product #RP-104663). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Palladin,uniProtId:Q8WX93-1,ncbiNodeId:9606,antigenRange:545-636,antigenLength:1383,antigenImageFileName:PA5-65160_Palladin_Q8WX93-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65160_Palladin_Q8WX93-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664239

Product Specific Information

Immunogen sequence: NCSYESMGESN NDHFQHFPPP PPILETSSLE LASKKPSEIQ QVNNPELGLS RAALQMQFNA AERETNGVHP SRGVNGLING KANSNKSLPT P

Highest antigen sequence identity to the following orthologs - mouse 83%, rat 83%.

Target Information

Palladin is a cytoskeletal protein required for organization of normal actin cytoskeleton. Palladin plays roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin may function as a scaffolding molecule with the potential to impact both actin polymerization as well as the assembly of existing actin filaments into higher-order arrays. It binds to proteins that bind to either monomeric or filamentous actin. It localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Palladin`s different isoforms may have functional differences. It is also involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.