Thermo Fisher Scientific SOD2 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MLSRAVCGTS RQLAPVLGYL GSRQKHSLPD LPYDYGALEP HINAQIMQLH HSKHHAAYVN NLNVTEEKYQ EALAKGDVTA QIALQPALKF NGGGHINHSI FWTNLSPNGG GEPKGELLEA IKRDFGSFDK FKEKLTAASV GVQGSGWGWL GFNKERGHLQ IAACPNQDPL QGTTGLIPLL GIDVWEHAYY LQYKNVRPDY LKAIWNVINW ENVTERYMAC KK

Target Information

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS).
SOD catalyzes the dismutation of superoxide radical anion (O₂⁻) to hydrogen peroxide, which is subsequently converted to water and oxygen by glutathione peroxidase and catalase.

There are several classes of SOD:

• SOD1 (Cu/Zn-SOD): Intracellular, homodimeric 32 kDa enzyme found in all eukaryotic species.
• SOD2 (Mn-SOD): Mitochondrial, tetrameric 80 kDa enzyme located in the mitochondrial matrix near the respiratory chain.
• SOD3 (EC-SOD): Extracellular, heparin-binding multimer expressed in lungs, vessel walls, and airways.
• SOD4 (CCS): Copper chaperone for SOD, delivers Cu to Cu/Zn-SOD and activates it through direct insertion.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.