Thermo Fisher Scientific Amylin Polyclonal Antibody
Rabbit polyclonal antibody against human Amylin (IAPP). Validated for IHC (paraffin) with 1:500–1:1,000 dilution. Affinity purified, unconjugated, and supplied in PBS with glycerol. Suitable for diabetes-related research on islet amyloid polypeptide.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IAPP. Recombinant protein control fragment (Product # RP-101656) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791294 |
Product Specific Information
Immunogen sequence:
LVHSSNNFGA ILSSTNVGSN TYGKRNAVEV LKREPLNYLP
Target Information
Islet, or insulinoma, amyloid polypeptide (Amylin) is commonly found in pancreatic islets of patients with type II diabetes mellitus or insulinoma. Although its role in diabetes development is recognized, a direct causative relationship remains under investigation. Amylin, similar to beta-amyloid (Abeta) in Alzheimer’s disease, can induce apoptotic cell death in certain cultured cells, which may contribute to type II diabetes pathogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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