Thermo Fisher Scientific DCLK1 Monoclonal Antibody (1751CT665.1.72)
인간 및 생쥐 반응성을 가진 DCLK1 단클론 항체로, Western blot에 최적화됨. Protein G로 정제된 액상 형태이며, PBS 버퍼에 0.09% sodium azide 포함. 신경세포 이동 및 미세소관 중합 관련 연구에 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1751CT665.1.72 |
| Immunogen | Recombinant protein of human DCLK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897655 |
Target Information
DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate their polymerization.
It also has a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent kinases, and a serine/proline-rich domain mediating protein-protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and has microtubule-polymerizing activity independent of its kinase function.
It plays roles in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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