Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI12B6), TrueMAB
인간 NPPB 단백질(아미노산 27–102)에 특이적인 마우스 모노클로날 항체. Western blot에 적합하며, 트루맙 형식으로 제공. 동결건조 형태로, PBS 및 trehalose 버퍼에 보존. 심혈관 연구 및 단백질 발현 분석에 활용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene is part of the natriuretic peptide family and encodes a secreted cardiac hormone. The protein undergoes two cleavage events — one intracellularly and another after secretion into the bloodstream. Its biological functions include:
- Natriuresis
- Diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
- Regulation of cardiovascular homeostasis
Elevated levels of this protein in blood indicate heart failure. Mutations are associated with postmenopausal osteoporosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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