ELK Biotechnology eIF4G (phospho-Ser1108) rabbit pAb
eIF4G (phospho-Ser1108) rabbit pAb는 인산화된 eIF4G 단백질을 검출하기 위한 항체로, WB에 적합합니다. 세포질에서 작용하며, 인간, 마우스, 랫에서 반응합니다. 고순도 IgG 폴리클로날 항체로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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eIF4G (phospho-Ser1108) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | eIF4G (phospho-Ser1108) rabbit pAb |
| Alternative Names | Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1), eIF-4G 1, eIF-4G1, p220 |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human eIF4G (Ser1108) |
| Host | Rabbit |
| Storage Conditions | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 180 kD |
| Gene ID (Human) | 1981 |
| Human Swiss-Prot No. | Q04637 |
| Cellular Localization | Cytoplasm, Stress granule |
| Species Reactivity | Human, Mouse, Rat |
Background
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
[Provided by RefSeq, Aug 2010]
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