ELK Biotechnology EPPI rabbit pAb
EPPI rabbit pAb는 인간, 생쥐, 랫트 시료에서 사용 가능한 다클론성 항체로, WB 분석에 적합합니다. 인간 EPPI 단백질 유래 펩타이드로 면역화되었으며, 정자 운동 억제 및 항균 활성 관련 연구에 활용됩니다. 안정적이며 -20°C에서 1년간 보관 가능합니다.
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제품명
EPPI rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human EPPI (AA range: 55–105) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 100526773 |
| Human Swiss-Prot No | O95925 |
| Cellular Localization | Isoform 1: Secreted. Cell surface. Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa. |
| Species Reactivity | Human; Mouse; Rat |
배경 (Background)
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
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