ELK Biotechnology EST4A rabbit pAb
Carboxylesterase 4A 단백질을 인식하는 rabbit polyclonal antibody로, WB에 적합합니다. 인간 및 마우스 시료에 반응하며, 약물 및 지방 대사 관련 연구에 활용 가능합니다. -20°C에서 1년간 보관 가능합니다.
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제품명
EST4A rabbit pAb
제품 개요
Carboxylesterase 4A (EC 3.1.1.-) 단백질을 인식하는 rabbit polyclonal antibody입니다. 다양한 xenobiotics 및 내인성 기질의 가수분해에 관여하는 효소 연구에 사용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | EST4A rabbit pAb |
| Alternative Names | Carboxylesterase 4A (EC 3.1.1.-) |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human EST4A (AA 441–491) |
| Host Species | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| GeneID (Human) | 283848 |
| Human Swiss-Prot No. | Q5XG92 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Mouse |
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2010]
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