ELK Biotechnology EST5A rabbit pAb
EST5A 단백질을 인식하는 토끼 폴리클로날 항체로, WB에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, carboxylesterase 계열 효소 연구에 유용합니다. 합성 펩타이드 면역원으로 제작되었으며 -20°C에서 1년 보관 가능합니다.
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제품명
EST5A rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human EST5A (AA 278–328) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 221223 |
| Human Swiss-Prot No. | Q6NT32 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism and may play a role in the blood-brain barrier system. This gene, also called CES5, is predominantly expressed in peripheral tissues including brain, kidney, lung, and testis. It encodes a secreted enzyme known as cauxin (carboxylesterase-like urinary excreted protein) due to its high levels in the urine of male domestic cats. The enzyme functions in regulating the production of a pheromone precursor and may contribute to lipid and cholesterol transfer processes within male reproductive fluids. Multiple transcript variants encoding different isoforms have been found for this gene.
(provided by RefSeq, Jun 2010)
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