ELK Biotechnology EXOC6 rabbit pAb
EXOC6 단백질을 인식하는 rabbit polyclonal antibody로, WB에 적합하며 Human, Mouse, Rat 시료에 반응합니다. 세포질 및 성장 콘 등에서 발현되는 EXOC6 단백질 검출에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology EXOC6 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | EXOC6 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human EXOC6 (AA range: 610–660) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 54536 |
| Human Swiss-Prot No. | Q8TAG9 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치 (Cellular Localization)
Cytoplasm, perinuclear region, cell projection (growth cone), midbody, midbody ring.
Perinuclear localization in undifferentiated cells; redistributes to growing neurites and growth cones during neuronal differentiation.
Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).
Background
The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product, which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast.
It is one of the components of a multiprotein complex required for exocytosis.
The 5′ portion of this gene and two neighboring cytochrome P450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA).
Alternative splicing and the use of alternative promoters result in multiple transcript variants.
A paralogous gene encoding a similar protein is present on chromosome 2.
[provided by RefSeq, Jan 2016]
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