
ELK Biotechnology FBW1B rabbit pAb
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| Product name: | FBW1B rabbit pAb |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500-2000 |
| Immunogen: | Synthesized peptide derived from human FBW1B AA range: 464-514 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 23291 |
| Human Swiss-Prot No: | Q9UKB1 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human; Mouse |
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