ELK Biotechnology FBXL4 rabbit pAb

제품명

FBXL4 rabbit pAb

제품 설명

FBXL4 단백질을 인식하는 토끼 폴리클로날 항체입니다. F-box 단백질 패밀리에 속하는 FBXL4는 세포주기 조절에 관여하며, 유비퀴틴화 복합체의 구성요소로 알려져 있습니다. 본 항체는 Western blot(WB) 분석에 적합합니다.

제품 정보

Background

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. (RefSeq, Jul 2013)