ELK Biotechnology FHR5 rabbit pAb
인간, 랫트, 마우스 반응성을 가진 FHR5 rabbit polyclonal antibody. WB 실험에 적합하며 1:500~1:2000 희석 권장. 인간 FHR5 유래 합성 펩타이드(AA 353-403)로 면역화. 60kD 밴드 관찰, -20°C에서 1년 보관 가능.
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ELK Biotechnology FHR5 rabbit pAb
제품 개요
FHR5 rabbit polyclonal antibody는 인간 FHR5 단백질을 인식하며, 웨스턴블롯(WB) 분석에 적합한 항체입니다. 본 항체는 인간 FHR5 유래 합성 펩타이드(AA 353-403)를 면역원으로 사용하여 제작되었습니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Product name | FHR5 rabbit pAb |
| Alternative Names | Complement factor H-related protein 5 (FHR-5) |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human FHR5 (AA range: 353–403) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| GeneID (Human) | 81494 |
| Human Swiss-Prot No | Q9BXR6 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5–7 having heparin binding and C-reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]
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