ELK Biotechnology Histone H2B (phospho-Ser14) rabbit pAb
Histone H2B (phospho-Ser14) 인산화 특이적 rabbit polyclonal 항체. WB에 적합하며 1:1000~2000 희석 권장. 핵 및 염색체 위치 단백질 검출에 사용. -20°C 보관 시 1년 안정.
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Histone H2B (phospho-Ser14) Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2B (phospho-Ser14) rabbit pAb |
| Alternative Names | Histone H2B type 1-H (Histone H2B.j) (H2B/j) |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human Histone H2B (Ser14) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 18 kD |
| Gene ID (Human) | 8345 |
| Human Swiss-Prot No. | Q93079 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Rat, Mouse |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is located in the large histone gene cluster on chromosome 6.
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