ELK Biotechnology HOME3 rabbit pAb
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| Product name: | HOME3 rabbit pAb |
| Applications: | WB |
| Recommended Dilutions: | WB 1：500-2000 |
| Immunogen: | Synthesized peptide derived from human HOME3 AA range: 243-293 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID（Human）: | 9454 |
| Human Swiss-Prot No: | Q9NSC5 |
| Cellular localization: | Cytoplasm . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Postsynaptic density of neuronal cells. . |
| Background: | This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009], |
| Species Reactivity: | Human; Mouse;Rat |
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