Thermo Fisher Scientific FKBP25 Polyclonal Antibody
FKBP25 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 인간·마우스·랫트 반응성. 연구용으로만 사용 가능.
- 카탈로그번호
- PA551470
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific FKBP25 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FKBP25 (Product #RP-88925) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641655 |
Product Specific Information
Immunogen sequence:
LPKKDIIKFL QEHGSDSFLA EHKLLGNIKN VAKTANKDHL VTAYNHLFET KRFKGTESIS KVSEQVKNVK LNEDKPKETK SEETLDEGPP KYTKSVLKKG DKTNFPKKGD VVHCWYTGTL QDGT
Antigen sequence identity:
- Mouse: 92%
- Rat: 94%
Target Information
The protein encoded by this gene is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds immunosuppressants FK506 and rapamycin, as well as histone deacetylases, transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and may be an important target molecule for immunosuppression by rapamycin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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