Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody
Thermo Fisher Scientific의 SDCCAG8 폴리클로날 항체로, 인간 SDCCAG8 단백질을 인식합니다. WB 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 저장용액에 40% 글리세롤 포함, 장기 보관은 -20°C 권장.
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Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SDCCAG8. Recombinant protein control fragment (Product #RP-93995). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647047 |
Product Specific Information
Immunogen sequence:
QLELEKLKLT YEEKCEIEES QLKFLRNDLA EYQRTCEDLK EQLKHKEFLL AANTCNRVGG LCLKCAQHEA VLSQTHTNVH MQTIERLVKE RDDLMSAL
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 76%
Target Information
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, and renal cancer tumors.
Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder characterized by dysplasia or degeneration of the kidney, retina, and cerebellum.
SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes, and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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