Thermo Fisher Scientific KCNJ3 Monoclonal Antibody (OTI2E4), TrueMAB
인간 KCNJ3 단백질(aa 279-501)을 인식하는 Mouse IgG1 단일클론 항체. Western blot, ICC/IF, Flow cytometry에 적용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 279-501 of human KCNJ3 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Their voltage dependence changes with extracellular potassium concentration — as external potassium increases, the channel opening voltage shifts to more positive potentials. Inward rectification results mainly from the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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