Thermo Fisher Scientific IL-29 Polyclonal Antibody
IL-29(Interferon lambda1)을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 항바이러스 연구 및 면역학적 분석에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-29 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–200 of human IFNL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2803809 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
IFN-lambdas constitute a novel family of interferons that mediate the induction of antiviral protection in a wide variety of cells.
There are three members in this family—lambda1, lambda2, and lambda3—also known as IL-29, IL-28A, and IL-28B, respectively.
Similar to type I IFNs, IFN-lambdas activate intracellular signaling to promote gene expression.
They mediate antiviral protection through a class II cytokine receptor complex composed of CRF2-12/IFN-lambdaR1 (unique to IFN-lambdas) and CFR2-4/IL-10R2 (shared with IL-10, IL-22, and IL-26 receptors).
IL-28 and IL-29 have been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells.
Dendritic cells differentiated by IFN-lambdas express high levels of MHC class I and II but low levels of costimulatory molecules, and can induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.