Thermo Fisher Scientific GM-CSF Polyclonal Antibody
GM-CSF 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 인간 시료 반응성. Protein A 및 항원 친화 크로마토그래피로 정제된 고품질 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 59–85 of the central region of human CSF2 (GM-CSF). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term; for long term, store at −20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541684 |
Target Information
The GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active protein exists as a homodimer in the extracellular space.
This gene is located in the chromosome region 5q31, a cluster associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in this cluster include interleukins 4, 5, and 13. GM-CSF is involved in promoting tissue inflammation, and elevated levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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