Thermo Fisher Scientific CDH18 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Target Information

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
Type II (atypical) cadherins are defined by their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth, and guidance.
Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner to connect cells and may contribute to the sorting of heterogeneous cell types.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.