Thermo Fisher Scientific CDH18 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CDH18. Validated for Western blot applications. Suitable for research use in studying cadherin-mediated cell adhesion and neural development. Supplied as a liquid, unconjugated form with 1 mg/mL concentration....
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- PA538855
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human CDH18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555448 |
Target Information
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain.
Type II (atypical) cadherins are defined by their lack of a HAV cell adhesion recognition sequence specific to type I cadherins.
This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth, and guidance.
Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner to connect cells and may contribute to the sorting of heterogeneous cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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