Thermo Fisher Scientific SOX17 Monoclonal Antibody (OTI2F9), Biotin, TrueMAB
SOX17 단백질을 인식하는 Biotin 결합 단클론 항체로, ELISA 및 Luminex 분석에 적합합니다. 인간 시료 반응성이 있으며, 고순도의 액상 형태로 제공됩니다. 생식 발달 및 Wnt 신호 조절 연구에 활용 가능합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1:250–1:1,000
Luminex (LUM)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 177–414 of human SOX17 produced in E. coli |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors.
It acts as a transcription regulator that binds target promoter DNA and bends the DNA.
SOX17 binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-'3, modulating transcriptional regulation via WNT3A and inhibiting Wnt signaling.
It promotes degradation of activated CTNNB1 and plays an essential role in embryonic development, including heart tube looping and definitive gut endoderm formation.
Mutations in the gene can cause vesicoureteral reflux.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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