Thermo Fisher Scientific OPRK1 Polyclonal Antibody
OPRK1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 및 랫드 시료에 반응합니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C, 장기 -20°C에서 보관 가능합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human Kappa Opioid Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551230 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bat, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig (94%).
Target Information
This gene encodes an opioid receptor, a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands and various synthetic opioids. Ligand binding inhibits adenylate cyclase activity and neurotransmitter release. This receptor plays roles in pain perception and mediating the hypolocomotor, analgesic, and aversive actions of synthetic opioids. Variations in this gene are associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been identified. A recent study provided evidence for translational readthrough and expression of an additional C-terminally extended isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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