Thermo Fisher Scientific MSL2 Monoclonal Antibody (OTI6C10), TrueMAB
MSL2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot에 최적화됨. 인간 MSL2 전체 길이 재조합 단백질을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C10 |
| Immunogen | Full length human recombinant protein of human MSL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16, which is implicated in the formation of higher-order chromatin structure.
Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at Lys-35 (H2BK34Ub), but not that of H2A.
This activity is greatly enhanced by heterodimerization with MSL1.
H2B ubiquitination in turn stimulates histone H3 methylation at Lys-4 (H3K4me) and Lys-79 (H3K79me), leading to gene activation, including that of HOXA9 and MEIS1.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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