Thermo Fisher Scientific VMP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human VMP1. Recombinant protein control fragment (Product #RP-102047). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VMP1,uniProtId:Q96GC9-1,ncbiNodeId:9606,antigenRange:136-235,antigenLength:406,antigenImageFileName:PA5-56555_VMP1_Q96GC9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56555_VMP1_Q96GC9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649442

Product Specific Information

Immunogen sequence: LYLGPHIASV TLAAYECNSV NFPEPPYPDQ IICPDEEGTE GTISLWSIIS KVRIEACMWG IGTAIGELPP YFMARAARLS GAEPDDEEYQ EFEEMLEHAE

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 99%.

Target Information

VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.