Thermo Fisher Scientific Histone Deacetylase 1 (HDAC1) Monoclonal Antibody (PCRP-HDAC1-1B7)
HDAC1 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체. 인간 시료에 반응하며 ICC, Flow, ELISA, IP 등 다양한 응용 가능. 고순도 Protein A/G 정제, PBS 버퍼에 보존. 연구용으로만 사용.
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Thermo Fisher Scientific Histone Deacetylase 1 (HDAC1) Monoclonal Antibody (PCRP-HDAC1-1B7)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-HDAC1-1B7 |
| Immunogen | Recombinant full-length human HDAC1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in regulating eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.
It interacts with retinoblastoma tumor-suppressor protein, forming a complex that controls cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effects on cell growth and apoptosis.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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