Thermo Fisher Scientific SEMA7A Monoclonal Antibody (1G1)
인간 SEMA7A 단백질을 인식하는 Mouse IgG2a 단클론 항체입니다. Western blot, ICC/IF, ELISA에 적합하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었고, PBS buffer에 보존제가 없습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G1 |
| Immunogen | SEMA7A (NP_003603, 536–633 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
EPHKECPNPK PDKAPLQKVS LAPNSRYYLS CPMESRHATY SWRHKENVEQ SCEPGHQSPN CILFIENLTA QQYGHYFCEA QEGSYFREAQ HWQLLPED
Target Information
CD108 (Sema7A) is a GPI-anchored semaphorin family member that enhances central and peripheral axonal growth and is required for proper axon track formation during embryogenesis.
CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration. In the immune system, it affects cell proliferation, chemotaxis, and cytokine release.
On erythrocytes, CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signals through its receptors — plexin C1 and beta1 integrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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