Thermo Fisher Scientific KSR2 Polyclonal Antibody, MaxPab
Human KSR2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화됨. 액상 형태이며 PBS buffer에 보관, -20°C에서 냉동 보관 필요. MEKK3 및 MAP3K 신호 조절 연구에 적합한 연구용 항체.
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Thermo Fisher Scientific KSR2 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KSR2 (NP_775869.2, 1–829 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MTDEQVCETV EKYGANREEC ARLNASLSCL RNVHMSGGNL SKQDWTIQWP TTETGKENNP VCPPEPTPWI RTHLSQSPRV PSKCVQHYCH TSPTPGAPVY THVDRLTVDA YPGLCPPPPL ESGHRSLPPS PRQRHAVRTP PRTPNIVTTV TPPGTPPMRK KNKLKPPGTP PPSSRKLIHL IPGFTALHRS KSHEFQLGHR VDEAHTPKAK KKSKPLNLKI HSSVGSCENI PSQQRSPLLS ERSLRSFFVG HAPFLPSTPP VHTEANFSAN TLSVPRWSPQ IPRRDLGNSI KHRFSTKYWM SQTCTVCGKG MLFGLKCKNC KLKCHNKCTK EAPPCHLLII HRGDPARLVR TESVPCDINN PLRKPPRYSD LHISQTLPKT NKINKDHIPV PYQPDSSSNP SSTTSSTPSS PAPPLPPSAT PPSPLHPSPQ CTRQQKNFNL PASHYYKYKQ QFIFPDVVPV PETPTRAPQV ILHPVTSNPI LEGNPLLQIE VEPTSENEEV HDEAEESEDD FEEMNLSLLS ARSFPRKASQ TSIFLQEWDI PFEQLEIGEL IGKGRFGQVY HGRWHGEVAI RLIDIERDNE DQLKAFKREV MAYRQTRHEN VVLFMGACMS PPHLAIITSL CKGRTLYSVV RDAKIVLDVN KTRQIAQEIV KGMGYLHAKG ILHKDLKSKN VFYDNGKVVI TDFGLFSISG VLQAGRREDK LRIQNGWLCH LAPEIIRQLS PDTEEDKLPF SKHSDVFALG TIWYELHARE WPFKTQPAEA IIWQMGTGMK PNLSQIGMGK EISDILLFCW AFEQEERPTF TKLMDMLEKL PKRNRRLSHP GHFWKSAEL
Target Information
KSR2는 serine/threonine kinase로서 MEKK3 및 COT의 활성 조절에 관여하며, MAP3K8 kinase 활성과 MAP3K8 매개 신호를 억제합니다. 또한 MAP3K3 매개 ERK, JNK, NF-κB 경로 활성화를 음성 조절하여 interleukin-8 생성 억제에 관여합니다.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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