Thermo Fisher Scientific ZHX2 Polyclonal Antibody
Thermo Fisher Scientific의 ZHX2 Polyclonal Antibody는 마우스 ZHX2 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot에 적합하며, 단백질 발현 연구 및 전사 억제 관련 연구에 활용됩니다. Protein A로 정제된 액상 항체로, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse ZHX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2692289 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 86%; Horse: 79%; Human: 79%; Mouse: 100%; Pig: 93%; Rabbit: 86%; Rat: 100%
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA).
ZHX1-3 are ubiquitously expressed proteins found in various tissues. They act as transcriptional repressors and localize to the nucleus.
ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), allowing the formation of homodimers or heterodimers.
Dimerization is not required for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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