Thermo Fisher Scientific DKC1 Recombinant Rabbit Monoclonal Antibody (JU34-32)
DKC1 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간 시료에 반응하며 HEK293 세포에서 발현된 재조합 항체입니다. Protein A로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU34-32 |
| Immunogen | Synthetic peptide within Human DKC1 aa 353–402 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848548 |
Product Specific Information
Positive Control: A431, rat brain tissue, human kidney tissue, mouse testis tissue.
Target Information
This gene is a member of the H/ACA snoRNPs gene family, which is involved in rRNA processing and modification. The H/ACA snoRNPs include NOLA1, NOLA2, and NOLA3 proteins. The encoded protein and these NOLA proteins localize to nucleoli and coiled bodies in the nucleus. Depletion of any of these proteins impairs 18S rRNA production and rRNA pseudouridylation. These proteins are also components of the telomerase complex. Mutations in this gene cause X-linked dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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