Thermo Fisher Scientific PLAGL2 Polyclonal Antibody
PLAGL2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography 방식으로 정제됨. PBS와 50% glycerol 용액에 보관되며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLAGL2 (Accession Q9UPG8), corresponding to amino acid residues R28–A78 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849817 |
Product Specific Information
Antibody detects endogenous levels of total PLAGL2.
Target Information
The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins includes PLAG1, ZAC1, and PLAG-like 2 (PLAGL2).
PLAG1 is the target gene for pleiomorphic adenomas of the salivary gland.
ZAC1 (PLAGL1) controls apoptosis and cell cycle arrest through separate pathways and acts as a transcriptional cofactor for nuclear receptors.
PLAGL2 belongs to the Krueppel C2H2-type zinc-finger protein family and contains six C2H2-type zinc fingers.
It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed, particularly in spleen, lung, and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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