Himedia HiKaryoXL Colcemid® Solution w/ 10µg per ml Colcemid in Phosphate Buffered Saline

Colcemid, also known as demecolcine, is a synthetic analog of colchicine. It is less toxic to cells than colchicine. Being a mitotic inbitor, colcemid binds to the tubulin protein and obstructs the spindle fibre formation. It effectively arrests cell in metaphase, allowing cell harvest and karyotyping to be performed. Colcemid is used to arrest different types of cells in metaphase like peripheral blood cells, amniotic fluid cells, fibroblasts, bone marrow cells and cells from chorion villus samples, etc. TCL133 is a sterile filtered solution of 10μg per ml of Colcemid in Phosphate Buffered Saline.