
Thermo Fisher Scientific TMEM70 Polyclonal Antibody
인간 TMEM70 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존. 미토콘드리아 ATP 합성 효소 생합성 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TMEM70. Recombinant protein control fragment (Product #RP-91012) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648722 |
Product Specific Information
Immunogen sequence:
KGYVIRLYHE ATTDTYKAIT YNAMLAETST VFHQNDVKIP DAKHVFTTFY AKTKSLLVNP VLFPNREDYI HLMGYDKEEF ILYMEETSEE KRHKDDK
- Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 71%
Target Information
TMEM70 is a mitochondrial protein involved in the biogenesis of ATP synthase in higher eukaryotes.
Mutations in TMEM70 cause neonatal onset hypotonia, hypertrophic cardiomyopathy, lactic acidosis, and 3-methylglutaconic aciduria (3-MGC-uria).
These conditions often lead to early death within six weeks of life, although some patients survive longer.
TMEM70 contains a conserved DUF1301 domain and two putative transmembrane regions, and is conserved across multicellular eukaryotes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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