Thermo Fisher Scientific Human LXR beta Synthetic Peptide
인간 LXRβ의 아미노 말단 14개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20886의 블로킹 펩타이드로 사용 가능합니다. 지질 항상성과 염증 조절 관련 연구에 적합합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1000
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the amino terminus of human LXR-B.
PEP-1000 can be used as a blocking peptide with polyclonal antibody PA5-20886.
Target Information
The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.
The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed.
Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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