Thermo Fisher Scientific SLC10A2 Polyclonal Antibody
SLC10A2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간과 마우스 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC10A2 (Accession Q12908), corresponding to amino acid residues P332–K348 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815655 |
Product Specific Information
Antibody detects endogenous levels of total ASBT.
Target Information
This gene encodes a sodium/bile acid cotransporter that mediates the uptake of intestinal bile acids by apical cells in the distal ileum. It plays a key role in cholesterol homeostasis as bile acids are the catabolic products of cholesterol metabolism.
Mutations in this gene cause primary bile acid malabsorption (PBAM) and may also be associated with liver and intestinal disorders such as familial hypertriglyceridemia (FHTG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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