Thermo Fisher Scientific beta-hydroxybutyryl-HIST1H2BC (Lys120) Polyclonal Antibody
Human HIST1H2BC 단백질의 Lys120 위치에서 beta-hydroxybutyryl 변형을 인식하는 Rabbit Polyclonal Antibody. ICC/IF 및 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태, 안정적인 PBS/glycerol buffer 구성. 연구용으로 적합.
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- PA5144337
- 판매단위
- pk
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Thermo Fisher Scientific beta-hydroxybutyryl-HIST1H2BC (Lys120) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of beta-hydroxybutyryl-Lys (120) derived from Human Histone H2B type 1-C/E/F/G/I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3093651 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
The protein exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This variant lacks a polyA tail but contains a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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(이미지 파일명: PA5-144337_HIST1H2BC_P62807-1_Rabbit.svg, PA5-144337_HIST1H2BC_P62807-1_Rabbit_PDP.jpeg)
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