Thermo Fisher Scientific Bacillus anthracis lethal factor Polyclonal Antibody
Bacillus anthracis 치명적 인자(Lethal Factor)에 특이적인 토끼 폴리클로날 항체로, WB, IHC, ICC, ELISA 등에 사용 가능. Protein A로 정제된 고순도 항체이며, -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- BS-12564R
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from Bacillus anthracis lethal factor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of Bacillus anthracis, the causative agent of anthrax. It consists of a cell-binding protein (Protective Antigen, PA) and two enzyme components (Edema Factor, EF, and Lethal Factor, LF). These components act together to exert their physiological effects. After endocytosis, the enzymatic components translocate into the cytoplasm, disrupting immune cell signaling and migration, and may induce cell lysis. Anthrax toxin enables the bacteria to evade the immune system, proliferate, and kill the host. Research on anthrax toxin provides insights into macromolecular assembly, protein translocation, pore formation, and endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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