Thermo Fisher Scientific Calpain 11 Polyclonal Antibody
Calpain 11 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 1:500–1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 인간 시료 반응성이 있으며 연구용으로 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CAPN11. Recombinant protein control fragment (Product # RP-94868) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790324 |
Product Specific Information
Immunogen sequence:
WELDEVNYAE QLQEEKVSED DMDQDFLHLF KIVAGEGKEI GVYELQRLLN RMAIKFKSFK TKGFGLDACR CMINLMDKDG SGK
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal and intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits and a common small regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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