Thermo Fisher Scientific FXYD2 Polyclonal Antibody
FXYD2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 유래 합성 펩타이드로 면역화됨. 비결합형 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human FXYD2 (amino acids 37–66, UniProt ID: P54710-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691605 |
Target Information
The human FXYD2 (pronounced fix-id) gene is located on chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA). The FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity.
The mammalian FXYD family maintains Na⁺ and K⁺ gradients between intracellular and extracellular environments, playing roles in renal Na⁺ reabsorption, muscle contraction, and neuronal excitability.
FXYDs are single-span membrane proteins sharing a 35 amino acid signature domain beginning with the sequence PFXYD, containing 7 invariant and 6 conserved amino acids.
Other family members include FXYD1 (PLM), FXYD3 (Mat8), FXYD4 (CHIF), and FXYD5 (RIC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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