Thermo Fisher Scientific CD122 Monoclonal Antibody (1G11C6)
Thermo Fisher Scientific CD122 Monoclonal Antibody (1G11C6)은 인간 CD122 단백질을 인식하는 Mouse IgG2b 형 단일클론 항체입니다. Western blot, Flow cytometry, ELISA에 사용 가능하며, 고순도 Protein G 정제 및 안정적인 PBS 용액 형태로 제공됩니다. 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G11C6 |
| Immunogen | Purified recombinant fragment of human CD122 (AA: extra 27–240) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090791 |
Target Information
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses and is primarily expressed in the hematopoietic system. It exists in three forms:
- Low affinity form: Monomer of the alpha subunit, not involved in signal transduction.
- Intermediate affinity form: Alpha/beta heterodimer.
- High affinity form: Alpha/beta/gamma heterotrimer.
Both intermediate and high affinity forms are involved in receptor-mediated endocytosis and mitogenic signal transduction. The CD122 gene encodes the beta subunit, a type I membrane protein. Dysfunction of CD122 is associated with diseases such as oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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