Thermo Fisher Scientific IL5RA Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HeLa, HepG2, HCT116
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

Interleukin 5 (IL-5) is a soluble T cell-derived factor that induces B cell and eosinophil growth and differentiation. IL-5 acts through the IL-5 receptor (IL-5R), composed of an alpha chain that binds IL-5 with low affinity and a beta chain that, together, form the high-affinity receptor complex. The cytoplasmic domains of both chains are essential for signal transduction, with the membrane-proximal proline-rich sequence of IL-5Rα being critical for IL-5–induced proliferative responses and activation of signaling proteins such as JAK1 and JAK2.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.