
Thermo Fisher Scientific IL5RA Polyclonal Antibody
Human IL5RA 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–339 of Human IL5 Receptor alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2545376 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Interleukin 5 (IL-5) is a soluble T cell-derived factor that induces B cell and eosinophil growth and differentiation. IL-5 acts through the IL-5 receptor (IL-5R), composed of an alpha chain that binds IL-5 with low affinity and a beta chain that, together, form the high-affinity receptor complex. The cytoplasmic domains of both chains are essential for signal transduction, with the membrane-proximal proline-rich sequence of IL-5Rα being critical for IL-5–induced proliferative responses and activation of signaling proteins such as JAK1 and JAK2.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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