Thermo Fisher Scientific XRCC6BP1 Polyclonal Antibody
Human XRCC6BP1 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용 전용.
- 카탈로그번호
- PA557403
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human XRCC6BP1. Recombinant protein control fragment (Product #RP-95848). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649700 |
Product Specific Information
Immunogen sequence:
CEDCNGNVSG GFDASTSQIV LCQNNIHNQA HMNRVVTHEL IHAFDHCRAH VDWFTNIRHL ACSEVRAANL SGDCSLVNEI
Sequence identity with orthologs:
- Mouse: 89%
- Rat: 86%
Target Information
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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