Thermo Fisher Scientific MEMO1 Polyclonal Antibody
MEMO1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 및 설치류 등 다양한 종에 반응. 액상 형태로 제공되며 -20°C에서 보관. 세포 이동 및 ERBB2 신호전달 연구에 유용.
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Thermo Fisher Scientific MEMO1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MEMO1 (aa 171–220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691136 |
Product Specific Information
This target displays homology in the following species:
Cow: 100% | Dog: 100% | Guinea Pig: 100% | Horse: 100% | Human: 100% | Mouse: 100% | Rabbit: 100% | Rat: 100% | Yeast: 90% | Zebrafish: 100%
Target Information
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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