Thermo Fisher Scientific GW182 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GW182 (TNRC6A) for WB and IP applications. Recognizes region 575–625 of TNRC6A. Unconjugated, liquid form, 1 mg/mL concentration. Suitable for RNAi and microRNA pathway research.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 6 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of human glycine-tryptophan protein of 182 kDa (TNRC6A, UniProt ID: Q8NDV7-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
TNRC6A is a member of the trinucleotide repeat containing 6 protein family.
This protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways.
It associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies.
Inhibition of TNRC6A expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please see the Entrez Gene record for additional references.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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