Thermo Fisher Scientific CXXC5 Polyclonal Antibody
CXXC5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 원숭이, 랫트 반응성. 고순도 친화성 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CXXC5 (Accession Q7LFL8), corresponding to amino acid residues P46–M96 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853639 |
Product Specific Information
Antibody detects endogenous levels of total CXXC5.
Target Information
CXXC5 is a zinc finger protein closely related to the DVL1-binding protein CXXC4 (Idax), and like CXXC4, it modulates the Wnt signaling pathway during development.
CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitating the response of stem cells to Wnt3a.
Recent reports suggest that CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together they are involved in the WNT/β-catenin pathway, playing a role in embryonic kidney development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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