Thermo Fisher Scientific CXCL17 Polyclonal Antibody
Mouse CXCL17 단백질을 인식하는 sheep 유래 polyclonal antibody로, Western blot 및 ELISA에 적합. 항원 친화 크로마토그래피로 정제되었으며, 보존제 무첨가 PBS 버퍼에 동결건조 형태로 제공. CXCL17 관련 면역 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse CXCL17/VCC-1 (Ser31–Leu119) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607448 |
Product Specific Information
- In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human CXCL17/VCC-1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
CXCL17 is a chemokine that acts as a chemoattractant for monocytes, macrophages, and dendritic cells. It primarily functions in mucosal tissues, attracting immune cells to the lungs. CXCL17 is involved in angiogenesis, tumor development, and exhibits anti-inflammatory activity in the stomach. It may play a role in innate defense against infections and activates the C-X-C chemokine receptor GPR35, inducing a transient increase in intracellular calcium levels. The 4-Cys form of CXCL17 shows greater chemoattractant potency than the 6-Cys form. Dysregulation of CXCL17 has been associated with diseases such as cholera.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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