
Thermo Fisher Scientific FASN Monoclonal Antibody (3B3-1D6)
FASN 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot, ICC/IF, ELISA에 적합합니다. Human 시료에 반응하며, 비결합(Unconjugated) 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, PBS buffer에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B3-1D6 |
| Immunogen | FASN (AAH07909, 1 a.a. – approximately 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS GLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG
Target Information
Fatty acid synthase (FASN)는 다기능 단백질로, NADPH 존재하에서 acetyl-CoA와 malonyl-CoA로부터 palmitate를 합성하여 장쇄 포화지방산을 생성합니다. 일부 암 세포주에서는 FASN 단백질이 estrogen receptor-alpha (ER-alpha)와 융합되어 N-말단의 FAS가 ER-alpha의 C-말단과 결합된 형태로 존재하기도 합니다.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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