Thermo Fisher Scientific CPS1 Monoclonal Antibody (2E4AE11)
CPS1 단백질을 인식하는 마우스 단클론 항체로 Western blot, ICC/IF, IP에 사용 가능. 인간 간 미토콘드리아 유래 면역원으로 제작. 비결합형 액상 포맷이며 4°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E4AE11 |
| Immunogen | Human liver mitochondria |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| RRID | AB_2535903 |
Target Information
The mitochondrial enzyme encoded by this gene catalyzes the synthesis of carbamoyl phosphate from ammonia and bicarbonate, representing the first committed step of the urea cycle. This process is critical for the removal of excess urea from cells. The encoded protein may also function as a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been identified, with the shortest isoform potentially not localized to the mitochondrion. Mutations in this gene are associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and venoocclusive disease following bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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